Anti-phospho-MAP4 (Ser941)抗体 YB--5438R报价/价格-抗体 Anti-

生物论坛 抗体

 Anti-phospho-MAP4 (Ser941)抗体

产品编号 YB-5438R 英文名称 phospho-MAP4 (Ser941) 中文名称 ***酸化微管相关蛋白4抗体 别    名 MAP4 (phospho S941); p-MAP4 (phospho S941); MAP4(phospho Ser941); DKFZp779A1753; MAP-4; MAP4; MAP4_HUMAN; MGC8617; Microtubule associated protein 4; Microtubule-associated protein 4; OTTHUMP00000210723; OTTHUMP00000210725; OTTHUMP00000210727; OTTHUMP00000210730.   规格价格 100ul/1580元 购买        大包装/询价 说 明 书 100ul   产品类型 ***酸化抗体  研究领域 细胞生物  信号转导  细胞周期蛋白  细胞骨架   抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse,  产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量 121kDa 细胞定位 细胞浆  性    状 Lyophilized or Liquid 浓    度 1mg/ml 免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human MAP4 around the phosphorylation site of Ser941:VG(p-S)TE  亚    型 IgG 纯化方法 affinity purified by Protein A 储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed PubMed 产品介绍 background: The MAP4 (Microtubule associated protein 4)is a non neuronal microtubule associated protein. It promotes microtubule assembly.The phosphorylation of the Pro rich region in the C-terminus negatively regulates MAP4 activity to promote microtubule assembly. Function: Non-neuronal microtubule-associated protein. Promotes microtubule assembly.  Subunit: Interacts with SEPT2; this interaction impedes tubulin-binding. Subcellular Location: Cytoplasm, cytoskeleton.  Post-translational modifications: Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Phosphorylation on Ser-787 negatively regulates MAP4 activity to promote microtubule assembly. Isoform 3 is phosphorylated on Ser-337 and Ser-338.  Similarity: Contains 4 Tau/MAP repeats.  SWISS: P27816 Gene ID: 4134 Database links:

Entrez Gene: 4134 Human

Entrez Gene: 17758 Mouse

Entrez Gene: 367171 Rat

Omim: 157132 Human

SwissProt: P27816 Human

SwissProt: P27546 Mouse

SwissProt: Q5M7W5 Rat

Unigene: 517949 Human

Unigene: 217318 Mouse

Unigene: 443428 Mouse

Unigene: 484451 Mouse

Unigene: 203122 Rat

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.