Anti-SLC27A5抗体 YB--4088R报价/价格-抗体 Anti-SLC27A5抗体 Yb

生物论坛 抗体

 

Anti-SLC27A5抗体

产品编号 YB-4088R 英文名称 SLC27A5 中文名称 脂肪酸转运蛋白5抗体 别    名 ACSB; ACSVL6; BA CoA ligase; BACS; BAL; Bile acid CoA ligase; Bile acyl CoA synthetase; Cholate CoA ligase; FACVL3; FATP 5; FATP5; Fatty acid Coenzyme A ligase very long chain 3; Fatty acid transport protein 5; Solute carrier family 27 (fatty acid transporter) member 5; Solute carrier family 27 member 5; Very long chain acyl CoA synthetase homolog 2; Very long chain acyl CoA synthetase related protein; VLACS related; VLACSR; VLCS H2; VLCSH2; S27A5_HUMAN.  
Specific References  (1)     |     bs-4088R has been referenced in 1 publications.
[IF=2.25] Han, Ying, et al. "Basis of aggravated hepatic lipid metabolism by chronic stress in high-fat diet-fed rat." Endocrine: 1-10.  WB ;  Rat.  
PubMed:24895043
 
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价 说 明 书 100ul  200ul 研究领域 肿瘤  免疫学  染色质和核信号  信号转导   抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human, Mouse, Rat, Cow, Horse, Sheep,  产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量 75kDa 细胞定位 细胞浆 细胞膜  性    状 Lyophilized or Liquid 浓    度 1mg/ml 免 疫 原 KLH conjugated synthetic peptide derived from human SLC27A5:251-350/690  亚    型 IgG 纯化方法 affinity purified by Protein A 储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed PubMed 产品介绍 background: SLC27A5 is an isozyme of very long chain acyl CoA synthetase (VLCS). It is an acyl CoA synthetase involved in bile acid metabolism and is proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. It is expressed in liver and associated with endoplasmic reticulum but not with peroxisomes. It seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, it also activates 3 alpha,7 alpha,12 alpha trihydroxy 5 beta cholestanate (THCA), the C27 precursor of cholic acid derived from the de novo synthesis from cholesterol. Function: Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein.  Tissue Specificity: Predominantly expressed in liver.  Similarity: Belongs to the ATP-dependent AMP-binding enzyme family. SWISS: Q9Y2P5 Gene ID: 10998 Database links:

Entrez Gene: 10998 Human

Entrez Gene: 26459 Mouse

Omim: 603314 Human

SwissProt: Q9Y2P5 Human

SwissProt: Q4LDG0 Mouse

Unigene: 292177 Human

Unigene: 10984 Mouse

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

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